Regorafenib Monohydrate

Regorafenib Monohydrate

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Regorafenib is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-?, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respectively.

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